At ten years old, Caruana became the youngest American to defeat a GM in a FIDE sanctioned event. By the age of twelve, he had earned his FIDE master title, won national scholastic championships, and two gold medals in the Pan-American Youth Championships. Caruana has since become one of the hottest players on the global chess scene. He crossed the super-elite rating of 2800 after winning the 42nd Sparkassen Chess Meeting in Dortmund, Germany. He was the eighth player in history to pass the 2800 barrier and secured the tournament win in the penultimate round without losing a game.
Since passing 2800 Caruana has impressed the world, beginning with winning the 2014 Sinquefield Cup, scoring eight and a half out of ten. He proceeded to win the U.S. Championships, place second at the Tata Steel Masters tournament, and lead the U.S. Olympiad team to a gold medal in Baku 2016. In 2018, Caruana won the 2018 Candidates tournament, making him the first American player to challenge the World Champion in a unified match. He continued that year by winning the Grenke Chess tournament, Norway Chess, and tying for first with Carlsen and Aronian in the Sinquefield Cup. His World Championship match against Carlsen saw a historic 12 drawn games, but he lost in the tiebreaks.